Known hypersensitivity to celecoxib, aspirin, other NSAIDs or to any of the excipients.
In patients who have demonstrated allergic-type reactions to sulfonamides.
In patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs including COX-2 inhibitors (see Precautions).
Peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery (see Precautions).
Patients with estimated creatinine clearance <30 ml/min.
Inflammatory bowel disease.
Congestive heart failure (NYHA II-IV).
Established ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease.